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Microbial Systems Cell Biology Group
KU Leuven


Spatiotemporal organization is a hallmark of all living systems and a requirement for faithful and efficient cellular replication. Our lab aims to uncover the governing principles and spatiotemporal mechanisms of cellular replication, thereby specifically focusing on the subcellular organization of the many processes required for growth and proliferation in microbes. We use microbes as model systems as they often exhibit short generation times, are small, unicellular, genetically tractable and easily culturable in a laboratory environment, and can have an enormous impact on humans and their health. We rely on a systems cell biology approach that combines genetics, molecular biology, fluorescence microscopy, quantitative image analysis, machine learning, data mining, biochemical techniques and bioinformatic analyses.

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